Subtle changes in motif positioning cause tissue- specific effects on robustness of an enhancer’s activity

HIGHLIGHTS

• who: Eileen E. M. Furlong from the (EMBL), Heidelberg, GermanyEditor: Michael Levine, University of California Berkeley, United States of America have published the article: Subtle Changes in Motif Positioning Cause Tissue- Specific Effects on Robustness of an Enhancer’s Activity, in the Journal: (JOURNAL) of March/19,/2013
• what: To examine these properties, the authors focused on ten motifs recognized by TFs that form part of a highly studied regulatory network that governs Drosophila mesoderm development , including the downstream effector TFs of Wingless (known as Wnt in vertebrates) and Dpp (BMP in vertebrates) signaling pathways . . .
  

   

  

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