HIGHLIGHTS
- who: Carmela Gallo from the , Pozzuoli, Napoli, Italy Department of Internal Medicine, University of Genova have published the research: Sulfavant A as the first synthetic TREM2 ligand discloses a homeostatic response of dendritic cells after receptor engagement, in the Journal: (JOURNAL)
- what: The authors aimed to investigate the effect of SULF A on DC maturation by a reverse pharmacology approach starting from the identification of TREM2 as molecular target of the sulfolipid. According to the current model of binding to TREM2 , this is expected to promote the interaction with the receptor thus explaining the stronger . . .
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