Supar to risk-stratify patients with malaria

HIGHLIGHTS

  • who: Veselina Stefanova from the Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada, Sandra ARotman have published the research: suPAR to Risk-Stratify Patients With Malaria, in the Journal: (JOURNAL) of 10/06/2022
  • what: The authors report an overview of urokinase/urokinase-type plasminogen activator receptor (uPA/uPAR) biology, review what is known about suPAR in pediatric malaria, and discuss the ability of suPAR to predict disease outcome and its potential as a druggable target. Given that dysregulated endothelial and immune activation contributes to the pathogenesis of severe falciparum malaria . . .

     

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