Super-enhancer-associated tmem44-as1 aggravated glioma progression by forming a positive feedback loop with myc

HIGHLIGHTS

  • who: Erbao Bian from the Cerebral Vascular Disease Research Center, Anhui Medical University, Hefei, China have published the research: Super-enhancer-associated TMEM44-AS1 aggravated glioma progression by forming a positive feedback loop with Myc, in the Journal: (JOURNAL)
  • what: The authors identified an uncharacterized lncRNA, TMEM44AS1, as a novel oncogenic factor in glioma cells through promoting cell growth in_vitro and in_vivo, migration, and invasion.
  • how: These results showed that Serpin Family B Member 3 (SerpinB3) was co-precipitated with in_vitro synthesized TMEM44-AS1 but not with antisense TMEM44-AS1 (Fig7A-B). These . . .

     

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