Supermolecule—drug conjugates based on acid-degradable polyrotaxanes for ph-dependent intracellular releaseof doxorubicin

HIGHLIGHTS

• who: Atsushi Tamura and colleagues from the Department of Organic Biomaterials, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), Kanda-Surugadai, Chiyoda, Tokyo, Japan have published the research: Supermoleculeu2014Drug Conjugates Based on Acid-Degradable Polyrotaxanes for pH-Dependent Intracellular Releaseof Doxorubicin, in the Journal: Molecules 2023, 28, x FOR PEER REVIEW after 48 of /2023/
• what: The authors aimed to apply acid-degradable PRXs as a drug carrier for achieving the intracellular release of drug-conjugated CDs through dissociation in acidic cellular environments . This study shows that acid-degradable PRXs act as . . .
  

   

  

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