Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis

HIGHLIGHTS

• who: Peder Rustøen Braadland from the Department of Molecular and Clinical Medicine, Wallenberg Laboratory Sahlgrenska Academy and University HospitalPA, USA have published the article: Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis, in the Journal: (JOURNAL)
• what: The authors show in two large independent cohorts that as PSC becomes more advanced, bile acid synthesis is increasingly suppressed. Taken together, the authors show that C4 may have clinical utility both as a sensitive marker of disease stage and to guide treatment strategies.
• future: Adding . . .
  

   

  

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