Suppression of endoplasmic reticulum stress-dependent autophagy enhances cynaropicrin-induced apoptosis via attenuation of the p62/keap1/ nrf2 pathways in neuroblastoma

HIGHLIGHTS

• who: . and collaborators from the Sichuan University, China have published the Article: Suppression of endoplasmic reticulum stress-dependent autophagy enhances cynaropicrin-induced apoptosis via attenuation of the P62/Keap1/ Nrf2 pathways in neuroblastoma, in the Journal: (JOURNAL)
• what: The authors investigated the anticancer efficacy of CYN against NB and further elucidated the role and potential mechanisms of CYN on ER stress, autophagy and the Nrf2 pathway in NB cells. The study demonstrated that CYN promoted autophagy by initiating autophagy and inhibiting autophagic flux. The authors aimed to clarify the relationship between autophagy and apoptosis in . . .
  

   

  

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