Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic spo11 allele

HIGHLIGHTS

• who: Homologous recombination and colleagues from the (UNIVERSITY) have published the Article: Suppression of genetic recombination in the pseudoautosomal region and at subtelomeres in mice with a hypomorphic Spo11 allele, in the Journal: (JOURNAL)
• what: The authors propose that specific suppression of homologous recombination at subtelomeres of the Gal4BD-Spo11 mice indicates the potential difference in the DSBs formed in these areas compared to DSBs in the rest of the genome.

SUMMARY

Although DMC1 foci were observed, their number was significantly reduced compared to wild_type. This problem is particularly pronounced when . . .

 



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