Suppression of mutant kirsten-ras (krasg12d)-driven pancreatic carcinogenesis by dual-specificity map kinase phosphatases 5 and 6

HIGHLIGHTS

  • who: Andrew M. Kidger from the (UNIVERSITY) have published the research: Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6, in the Journal: (JOURNAL) of 13/04/2022
  • what: This model has been widely used to study loss or mutation of tumour suppressor loci found in human pancreatic cancers, with such compound strains resulting in accelerated pancreatic tumour progression and in the induction of invasive and metastatic cancer .
  • how: Animal work was carried out in accordance with the Animal (Scientific Procedures) Act under PPL . . .

     

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