Suppression of the necroptotic cell death pathways improves survival in smn2b/- mice

HIGHLIGHTS

  • who: Rashmi Kothary from the Delaware State University, United States have published the research work: Suppression of the necroptotic cell death pathways improves survival in Smn2B/- mice, in the Journal: (JOURNAL)
  • what: The study shows that necroptosis plays a role in muscle fiber size indicating an intrinsic mechanistic relevant Frontiers in Cellular Neuroscience frontiersin.org 10.3389/fncel.2022.972029 Tissue processing and staining in skeletal muscle development. This model has an SMA phenotype comparable to the one in the Smn2B/- mice.
  • how: NMJs were quantified as either normal or displaying neurofilament accumulation . . .

     

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