Suppression of wild-type rhodopsin maturation by mutants linked to autosomal dominant retinitis pigmentosa*

HIGHLIGHTS

  • who: Rahul S. Rajan from the (UNIVERSITY) have published the research: Suppression of Wild-type Rhodopsin Maturation by Mutants Linked to Autosomal Dominant Retinitis Pigmentosa*, in the Journal: (JOURNAL) of October/27,/2004
  • what: In this experiment, as in all of the experiments reported here, the two rhodopsin plasmids were introduced at equal concentration, matching the ratio of the two alleles present in the genome of ADRP heterozygotes.
  • how: The data indicated that this dominant interference results from a direct physical interaction between mutant and wild-type proteins 1284 This is an Open . . .

     

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