Suramin binds and inhibits infection of sars-cov-2 through both spike protein-heparan sulfate and ace2 receptor interactions

HIGHLIGHTS

• who: Paul S. Kwon from the Rensselaer Polytechnic Institute National University have published the Article: Suramin binds and inhibits infection of SARS-CoV-2 through both spike protein-heparan sulfate and ACE2 receptor interactions, in the Journal: (JOURNAL) of 31/03/2023
• what: The authors examined the ability of suramin to bind to RBDs of several SARS-CoV-2 variants and elucidated the mechanism by which this potential repositioned drug may serve to inhibit viral entry and propagation. The authors show that the synthetic polyanionic drug suramin effectively binds to the RBD of the SARS . . .
  

   

  

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