Surface-sampling mass spectrometry to study proteins and protein complexes

HIGHLIGHTS

  • who: Kei F. Carver Wong and collaborators from the SchoolUniversity of have published the Article: Surface-sampling mass spectrometry to study proteins and protein complexes, in the Journal: (JOURNAL) of 29/03/2023
  • what: This approach has been the most studied approach to date for intact proteins and non-covalent complexes, most likely owing to its sensitivity.

SUMMARY

    Since the introduction of MALDI in the late eighties, demonstrating intact protein analysis up to 67 kDa using UV lasers, its use has become commonplace for surface analysis and imaging of biomolecules. Although . . .

     

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