Surface treatment with hydrophobic coating reagents (organosilanes) strongly reduces the bioactivity of synthetic amorphous silica in vitro

HIGHLIGHTS

• who: Martin Wiemann from the Erlangen-Nu00fcrnberg, Germany University of Brescia, Italy have published the paper: Surface Treatment With Hydrophobic Coating Reagents (Organosilanes) Strongly Reduces the Bioactivity of Synthetic Amorphous Silica in vitro, in the Journal: (JOURNAL)
• what: The authors showed that surface-treated highly hydrophobic SAS elicits neither cytotoxic nor pro-inflammatory effects in alveolar macrophages in_vitro. While organosilane treatment can also dampen the bioactivity of crystalline silica , the authors propose that the mechanism by which the in_vitro bioactivity of SAS is ruled out not only involves the inactivation of silanol groups but also . . .
  

   

  

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