HIGHLIGHTS
SUMMARY
This international multicenter retrospective cohort study included patients from 31 centers in 19 European countries and the United_States undergoing pancreatectomy after preoperative FOLFIRINOX chemotherapy. The study included 423 patients who underwent pancreatectomy after a median of six (IQR 5-8) preoperative cycles of FOLFIRINOX. The median OS was 38 months (95% confidence interval 34-42 months) for BRPC and 33 months (95% CI 27-45 months) for LAPC. Many centers currently perform surgery for selected patients with locally advanced pancreatic cancer (LAPC) after several cycles of preoperative FOLFIRINOX chemotherapy comprising 5-fluorouracil, oxaliplatin, irinotecan . . .
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