Susceptibility-induced internal gradients reveal axon morphology and cause anisotropic effects in the diffusion-weighted mri signal

HIGHLIGHTS

• What: With in silico experiments, the authors show that the susceptibility-induced orientation-dependence trends for the intraaxonal SE and PGSE signals are specific to the morphological characteristics expressed in an axon population. The authors focus on the results for SE experiments shown in Fig 1b where the trends are observed most clearly. The authors show that the orientation-dependence trend of MD and AD observed in the corpus callosum and cingula of an ex vivo monkey brain corresponds to that observed for the numerical C5 axons (XNH-segmentation from an ex vivo monkey corpus callosum expressing . . .
  

   

  

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