Sustained chk2 activity, but not atm activity, is critical to maintain a g1 arrest after dna damage in untransformed cells

HIGHLIGHTS

• who: Iraia García-Santisteban from the (UNIVERSITY) have published the research work: Sustained CHK2 activity, but not ATM activity, is critical to maintain a G1 arrest after DNA damage in untransformed cells, in the Journal: (JOURNAL)
• what: The authors examine the impact of ATM and activities on G1 checkpoint maintenance in untransformed cells after DNA damage caused by DSBs. The authors show that ATM becomes dispensable for G1 checkpoint maintenance as early as 1 h after DSB induction. The authors show that activity is lost in cells that recover from the G1 arrest pointing . . .
  

   

  

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