Sustained ifn signaling is associated with delayed development of sars-cov-2-specific immunity

HIGHLIGHTS

  • What: The authors show that SARS-CoV-2-infected patients experiencing high, sustained IFN signaling have a delayed generation of Spike-specific CD4+ T_cells and RBD-specific B cells.
  • Who: Elsa Brunet-Ratnasingham from the (UNIVERSITY) have published the research: Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity, in the Journal: (JOURNAL)
  • How: For unsupervised data characterization the authors considered these 14 measurements in cross-sectional samples taken at DSO11 (+/- 4 days n=242) (Fig 1A). A similar observation was made for sex (Fig S1JKL). To account . . .

     

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