HIGHLIGHTS
- who: Jose R. Hombrebueno from the Centres University have published the research: Sustained intraocular VEGF neutralization results in retinal neurodegeneration in the Ins2Akita diabetic mouse, in the Journal: Scientific Reports Scientific Reports
- what: The authors showed that multiple intravitreal injections of anti-VEGF antibody resulted in significant neuroretinal degeneration and vascular leakage in Ins2Akita diabetic mice. The differences in the affinity of the anti-mouse VEGF antibody used in this study compared to those specific clinical formulations (e_g Bevacizumab or Ranibizumab) make it difficult to predict to what level the VEGF neutralization is harmful to . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.