Sustained therapeutic effect of an anti-in ammatory peptide encapsulated in nanoparticles on ocular vascular leakage in diabetic retinopathy

HIGHLIGHTS

• who: December and collaborators from the Alabama State University, United States have published the research: Sustained therapeutic effect of an anti-in ammatory peptide encapsulated in nanoparticles on ocular vascular leakage in diabetic retinopathy, in the Journal: (JOURNAL)
• what: This study demonstrated that PEDF34-NP attenuated the increase of np-u03b2-catenin, an essential effector of the canonical Wnt signaling pathway, in diabetic retina. This study demonstrated that an intravitreal injection of an anti-antiangiogenic peptide of PEDF encapsulated with PLGA polymer displayed potent effects on retinal inflammation, vascular leakage, and neovascularization over 4 weeks . . .
  

   

  

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