Sustained tnf signaling is required for the synaptic and anxiety-like behavioral response to acute stress

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  • who: Gina M. Kemp from the , Animals All experiments were done using adult C BL/, male mice, week old for behavioral experiments and, week old for electrophysiology experimentsTNF homozygous knockout (TNF-/- mice), obtained from Jackson Labs, were bred in house, and compared with wild-type (WT) mice of the same background strain (C BL/ J) also bred in house. The in-house WT and TNF-/- lines were periodically backcrossed. In some cases, WT C BL/, mice were obtained from Charles River, in which case they were housed in the animal facility for at least one week prior . . .

     

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