Switchable car t cell strategy against osteosarcoma

HIGHLIGHTS

  • who: Laura Hidalgo from the Cellular Biotechnology Unit, Instituto de Investigaciu00f3n de Enfermedades Raras, Instituto de Salud Carlos III (ISCIII), Madrid, Spain have published the research work: Switchable CAR T cell strategy against osteosarcoma, in the Journal: (JOURNAL)
  • what: The authors report a switchable cell strategy based on anti-FITC cells and a switch molecule conjugated with FITC for targeting (OS) tumors. The authors evaluate the capacity of an monoclonal antibody conjugated with FITC (anti-B7-H3-FITC mAb) to control the antitumor activity of anti-FITC cells. The authors demonstrate that anti-B7-H3 . . .

     

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