HIGHLIGHTS
- who: Arjan Hazegh Nikroo et al. from the (UNIVERSITY) have published the paper: Switchable Control of Scaffold Protein Activity via Engineered Phosphoregulated Autoinhibition, in the Journal: (JOURNAL) of June/29,/2022
- what: We presented a modular strategy to introduce reversible control over scaffold protein activity.
- how: The authors presented a modular strategy to introduce reversible control over scaffold protein activity.
SUMMARY
By integrating two key signaling mechanisms, scaffold-mediated signaling and phosphorylation, this approach allows for the bidirectional regulation of 14-3-3 scaffolding activity. ■ SCAFFOLD DESIGN AND SYNTHESIS . . .
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