HIGHLIGHTS
- who: Shilpashree Mallesh and collaborators from the Department of Surgery, University Hospital of Bonn, Bonn, Germany have published the paper: Sympathetic Innervation Modulates Mucosal Immune Homeostasis and Epithelial Host Defense, in the Journal: Cells 2022, 11, 2606. of /2022/
- what: The authors aimed to assess the molecular and functional role of the SNS in mucosal homeostasis by the use of a chemical sympathectomy (cSTX) approach based on the application of 6-hydroxydopamine (6-OHDA), an effective model of intestinal muscularis SNS denervation, was recently shown to be superior to both genetic ablations of AR activation . . .
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