HIGHLIGHTS
- who: Synaptic Strength et al. from the France, Department of Applied Mathematics, Tel Aviv University, Tel Aviv, Israel have published the article: Synapse Geometry and Receptor Dynamics Modulate Synaptic Strength, in the Journal: (JOURNAL) of August/25,/2011
- what: The authors show that in addition to the vesicular release probability due to variations in their release locations and the AMPAR distribution the postsynaptic current amplitude has a large variance making a synapse an intrinsic unreliable device. The authors demonstrate that perisynaptic microdomains located outside the PSD impacts transmission by regulating the number of desensitized receptors . . .
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