Synaptic biomarkers in the cerebrospinal fluid associate differentially with classical neuronal biomarkers in patients with alzheimer’s disease and frontotemporal dementia

HIGHLIGHTS

  • who: Shreyasee Das from the (UNIVERSITY) have published the research: Synaptic biomarkers in the cerebrospinal fluid associate differentially with classical neuronal biomarkers in patients with Alzheimeru2019s disease and frontotemporal dementia, in the Journal: (JOURNAL)
  • what: This pilot study indicated that the synaptic biomarkers SNAP25, VAMP2, and Ng were not specific for AD, as they were also elevated in the heterogeneous FTD group compared to SCD.
  • how: To select a biomarker panel for each diagnostic group comparison the authors used Wald`s backward logistic regression on the synaptic biomarkers.

SUMMARY

     

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