HIGHLIGHTS
- What: The authors investigate the progressive loss of synaptic integrity in adult Drosophila NMJs located within the Dorsal Longitudinal Muscles (DLMs) of the thorax as well as the Ventral Abdominal Muscles (VAMs) with age. The authors demonstrate that the synaptic defects observed in Dystrophin mutants are recapitulated by RNAi-mediated knockdown within muscle tissue, highlighting the requirement of Dystrophin within muscles to maintain presynaptic integrity.
- Who: Jessica M. Sidisky from the Agnes Scott College, United States University of Pennsylvania, United States have published the research work: Synaptic defects in a drosophila model of muscular dystrophy . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.