HIGHLIGHTS
- who: Anna Karpova from the School of Biosciences, Neuroscience and Mental Health Research Institute, Cardiff University, Cardiff, UK, Leibniz Group have published the article: Synaptic GluN2B/CaMKII-α Signaling Induces Synapto-Nuclear Transport of ERK and Jacob, in the Journal: (JOURNAL)
- how: For detection and quantification of pJacob-S180 nuclear immunoreactivity after high frequency stimulation the authors utilized published protocols for immunohistochemical stainings (IHC/Karpova et_al 2013).
SUMMARY
In recent years signaling from synapse-to-nucleus has gained increasing attention and the hypothesis that nuclear gene_expression is controlled by a fast Ca2 . . .
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