Synergistic effect of pyrvinium pamoate and posaconazole against cryptococcus neoformans in vitro and in vivo

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  • who: Yali Li from the Jingzhou Hospital Affiliated to Yangtze University, China have published the Article: Synergistic effect of pyrvinium pamoate and posaconazole against Cryptococcus neoformans in vitro and in vivo, in the Journal: (JOURNAL)
  • what: In the present study, the antifungal efficacy of PP alone and in combination with triazoles and AmB against C. neoformans were investigated both in_vitro and in_vivo. The experiment was repeated triplicate using larvae from different batches. obtained from patients with cryptococcal meningitis. This study provides an example of a drug repurposing strategy that PP can be used in the . . .

     

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