Synergistic interactions of repurposed drugs that inhibit nsp1, a major virulence factor for covid-19

HIGHLIGHTS

• who: Hung-Teh Kao from the (UNIVERSITY) have published the research work: Synergistic interactions of repurposed drugs that inhibit Nsp1, a major virulence factor for COVID-19, in the Journal: Scientific Reports Scientific Reports
• what: The two functional sites within Nsp1 (described above) were the focus of this in silico screen: the RNA groove in the N-domain and the C-terminal alpha-loop- | Vol:.(1234567890) 12:10174 | Individual compounds partially reverse Nsp1 toxicity.
• how: It is noteworthy that some of the candidates selected for this analysis were identified in previous in silico . . .
  

   

  

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