Synergistic therapeutic effects of low dose decitabine and ny-eso-1 specific tcr-t cells for the colorectal cancer with microsatellite stability

HIGHLIGHTS

• who: Ganjun Yu and collaborators from the Department of Immunology, College of Basic Medicine and National Key Laboratory of Medical Immunology, Naval Medical, Shanghai, China have published the paper: Synergistic Therapeutic Effects of Low Dose Decitabine and NY-ESO-1 Specific TCR-T Cells for the Colorectal Cancer With Microsatellite Stability, in the Journal: (JOURNAL)
• what: Western blot analysis was conducted to investigate whether NY-ESO-1 mRNA level correlates with protein expression.
• how: Data showed that DAC could change the TAA expression in MSS CRC cell lines which suggested the enhanced immunogenicity . . .
  

   

  

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