Synthesis and evaluation of a non-peptide small-molecule drug conjugate targeting integrin α β

HIGHLIGHTS

• who: Non-Peptide Small-Molecule Drug and colleagues from the Organic and Bioorganic, Department of, Bielefeld University, Bielefeld, Germany have published the paper: Synthesis and Evaluation of a Non-Peptide Small-Molecule Drug Conjugate Targeting Integrin u03b1 u03b2, in the Journal: (JOURNAL)
• what: The RGD mimetic containing SMDC 18 inhibits integrindependent cell adhesion, which was shown for WM115 cells presenting the integrin u03b1Vu03b23.

SUMMARY

In this connection, antibody-drug conjugates (ADCs) (Gerber et_al, 2009; Chari et_al, 2014; Deneka et_al, 2019; Hoppenz et_al, 2020; Khongorzul et_al, 2020) and small-molecule drug conjugates . . .

 



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