HIGHLIGHTS
- who: Yothawathorn Pariyawongsakul et al. from the Graduate School of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand have published the research work: Synthesis and Evaluation of Anticonvulsant Activity of 6,8-Dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline in PTZ-Induced Seizure Model in Mice, in the Journal: (JOURNAL)
- what: Since there was the study showed that mono-substitution of methoxy showed lower efficacy than the corresponding 6,7-disubstituted derivative as one chemical feature of model is not mapped. The authors designed to synthesize IV with the introduction of 6,8-dimethoxy . . .
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