Synthesis and evaluation of technetium-99m-labeled ph (low) insertion peptide variant 7 for early diagnosis of mda-mb-231 triple-negative breast cancer by targeting the tumor microenvironment

HIGHLIGHTS

• who: Yuehua Chen from the Soochow University, China have published the research work: Synthesis and Evaluation of Technetium-99m-Labeled pH (Low) Insertion Peptide Variant 7 for Early Diagnosis of MDA-MB-231 Triple-Negative Breast Cancer by Targeting the Tumor Microenvironment, in the Journal: (JOURNAL)
• what: Tc-pHLIP (Var7) has a high radiochemical yield and high stability and shows high accumulation in TNBC.
• future: In future studies the authors will consider changing the characteristics of probe molecules (such as molecular weight amino_acid sequence and charge number) to reduce their binding to plasma_proteins . . .
  

   

  

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