Synthesis, antiproliferative effect and in silico logp prediction of bim-23052 analogs containing tyr instead of phe

HIGHLIGHTS

• who: Dancho Danalev et al. from the Biotechnology Department, University of Chemical Technology and Metallurgy, Kliment Ohridski Blvd have published the paper: Synthesis, Antiproliferative Effect and In Silico LogP Prediction of BIM-23052 Analogs Containing Tyr Instead of Phe, in the Journal: Pharmaceutics 2023,The 15, 1123 antiproliferative of /2023/
• what: Synthetic SST analogs that have a much longer half-life than the endogenous SST are more useful in the management of acromegaly and numerous neuroendocrine tumors.
• how: This investigation revealed that the analog with one Phe(4-F) residue in the prianalogs . . .
  

   

  

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