HIGHLIGHTS
- who: . and colleagues from the University of Pisa, Italy have published the research work: Synthesis, bioactivity, and molecular docking of novel arylpiperazine derivatives as potential AR antagonists, in the Journal: (JOURNAL)
- what: In this work, 22 novel arylpiperazine derivatives were designed and synthesized, and their biological evaluation and molecular docking were reported.
- how: These results indicated that the ARbinding affinity may play a key role in promoting the AR antagonistic activity and these arylpiperazine derivatives may be efficient AR antagonists for PCa treatment.
SUMMARY
Prostate cancer (PCa) is one . . .
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