Synthesis, characterization and antimicrobial and anticancer evaluations of some novel heteroannulated difuro[3,2-c:3′,2′-g]chromenes

HIGHLIGHTS

• What: The aim of this study was directed to synthesize a novel class of annulated compounds containing difur chromene. condensation of o-aminoacetyl derivative 3 was performed with some active methylene ketones namely 1 3-cyclohexanediones pyrazolones 1 3-thiazolidinones and barbituric acids furnished furochromenofuroquinolines furochromenofuropyrazolopyridines furochromenofurothiazolopyridines and furochromenofuropyridopyrimidines respectively. This study aimed to investigate chemical reactivity of compound 3 toThe current study aimed to investigate thethe chemical reactivity of compound 3 towards This study aimed ketones to investigate theachemical reactivity of compound com3 towards some cyclic methylene to create novel series of heteroannulated some cyclic methylene . . .
  

   

  

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