Synthesis, chiral resolution and enantiomers absolute configuration of 4-nitropropranolol and 7-nitropropranolol

HIGHLIGHTS

  • who: Rosa Sparaco and collaborators from the Department of Pharmacy, University of Naples Federico II, Via DMontesano, Naples, Italy have published the research work: Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol, in the Journal: Molecules 2023, 57 of /2023/
  • what: Because enantiomers may not share the same discovered for endogenous catecholamines, the authors synthesized 4-nitro- and 7-nitropropranolol. pharmacologic profile, to discover differences in nitration by the endothelium of These propranolol derivatives will be used as probes to evaluate the possible nitration different enantiomers of the same compound . . .

     

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