HIGHLIGHTS
- who: Nahal Shayegan from the Tehran University of Medical Sciences, Shiraz, Iran have published the article: Synthesis, in vitro u03b1-glucosidase inhibitory activities, and molecular dynamic simulations of novel 4-hydroxyquinolinone-hydrazones as potential antidiabetic agents, in the Journal: Scientific Reports Scientific Reports
- what: In continuation of the work to design u03b1-glucosidase inhibitors, compounds 6a-o were designed and synthesized.
- how: The results showed that 6m and 6l bind to the active_site on the enzyme and compete with the substrate for binding to the active_site.
SUMMARY
NMR results . . .
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