Synthesis of benzofuran derivatives via rearrangement and their inhibitory activity on acetylcholinesterase

HIGHLIGHTS

• who: Xiang Zhou 1 from the Department of Natural Medicinal Chemistry, China Pharmaceutical University, Tong Jia have published the paper: Synthesis of Benzofuran Derivatives via Rearrangement and Their Inhibitory Activity on Acetylcholinesterase, in the Journal: Molecules 2010, 15, 8593-8601 of 15/09/2010
• what: By linking a substituted phenylpiperazine moiety to the benzofuran backbone conformationally restricted derivatives that are as potential inhibitors of AChE for treating AD were synthesized.

SUMMARY

Benzofuran derivatives are a major group of biologically active heterocycles, which are usually important constituents of plant extracts used in . . .

 



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