Synthesis of c6-modified mannose 1-phosphates and evaluation of derived sugar nucleotides against gdp-mannose dehydrogenase

HIGHLIGHTS

  • who: Sanaz Ahmadipour and colleagues from the The University of Manchester, Princess Street, Manchester, BG, UK have published the article: Synthesis of C6-modified mannose 1-phosphates and evaluation of derived sugar nucleotides against GDP-mannose dehydrogenase, in the Journal: (JOURNAL)
  • what: The authors attempted to Scheme 1: Syntheses of C6-modified mannose 1-phosphates 13 and 17.

SUMMARY

    The opportunistic Gram-negative pathogen, Pseudomonas aeruginosa (PA), becomes the dominant pathogen in patients suffering from cystic fibrosis (CF) and causes a chronic respiratory infection that infects more than 80% of those . . .

     

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