Synthesis of new diphenyl urea-clubbed imine analogs and its implications in diabetic management through in vitro and in silico approaches

HIGHLIGHTS

• who: Anam Rubbab Pasha from the InstitutZakariya University have published the article: Synthesis of new diphenyl urea-clubbed imine analogs and its Implications in diabetic management through in vitro and in silico approaches, in the Journal: Scientific Reports Scientific Reports
• what: Type II diabetes is a serious health issue with high glycemic effect and can be controlled by u03b1-glucosidase inhibitors as therapeutic approach.

SUMMARY

For instance, compound 3l with meta-chloro group exhibited decreased inhibitory potential than 3a ­(IC50=70.17 ± 1.34 µM) of group A. However, compound 3m . . .

 



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