Synthesis of novel c/d ring modified bile acids

HIGHLIGHTS

• who: Roselis A. Landaeta Aponte and colleagues from the Ferrier Research Institute, Victoria University of Wellington, Lower Hutt , have published the research: Synthesis of Novel C/D Ring Modified Bile Acids, in the Journal: Molecules 2022, 2364 of /2022/
• what: This study has resulted in bile acid analogues with altered C/D ring conformations, which are currently being investigated for their ability to selectively activate the bile acid receptors FXR and TGR5.
• how: [42].Hydrolysis Hydrolysisof ofmethyl methylester ester29 29gave gaveits itscorresponding corresponding philicity which X-ray crystal data werecrystal obtained confirming formation . . .
  

   

  

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