Synthetic design and biological evaluation of new p53-mdm2 interaction inhibitors based on imidazoline core

HIGHLIGHTS

• who: Daniil R. Bazanov and colleagues from the Department of Chemistry, MVLomonosov Moscow State University, Moscow, Russia have published the Article: Synthetic Design and Biological Evaluation of New p53-MDM2 Interaction Inhibitors Based on Imidazoline Core, in the Journal: Pharmaceuticals 2022, 15, x FOR PEER REVIEW of /2022/
• what: The authors propose a novel modification of previously found imidazolines to increase their biological effect using the 2,4,5tris(alkoxyphenyl)imidazoline core.
• how: The authors have applied a simple approach of two-step synthesis of imidazoline-based alkoxyaryl compounds which are able to . . .
  

   

  

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