HIGHLIGHTS
- who: . et al. from the Laboratory of Medical Genetics, Faculty of Biology and Environmental Protection, University of Lodz, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA have published the Article: Synthetic Lethality Targeting Polθ, in the Journal: Genes 2022, 1101 of /2022/
- what: In the authors' opinion, the main interest should be focused on the type of tumor with alterations to the HR genes since the studies showed that cells of this type are ‘hyperdependent' on Polθ mediated repair (like with PARP1).
SUMMARY
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