Synthetic mimetics assigned a major role to ifnar2 in type i interferon signaling

HIGHLIGHTS

  • who: TYPE and collaborators from the Washington University in StLouis, United States have published the research: Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling, in the Journal: (JOURNAL)
  • what: A time course experiment was carried out to investigate the dynamics of STAT1 phosphorylation in Ba/ F3-gp130-VGmIFNAR1-VCmIFNAR2 cells stimulated with IFNu03b14 or GC. The authors focused on STAT1 and STAT2 phosphorylation as read-out of synthetic IFNAR activation because these are characteristic for type I IFNs.
  • how: Data analysis was conducted using FCS Express 7 (De . . .

     

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