Synthetic phosphoethanolamine-modified oligosaccharides reveal the importance of glycan length and substitution in biofilm-inspired assemblies

HIGHLIGHTS

• who: Theodore Tyrikos-Ergas from the Max Planck Institute University of have published the article: Synthetic phosphoethanolamine-modified oligosaccharides reveal the importance of glycan length and substitution in biofilm-inspired assemblies, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors report the synthesis by automated glycan assembly27 (AGA) of nine pEtN cellulose oligosaccharides with varying chain lengths, degrees and patterns of pEtN substitution.
• how: As epitome for the protein part the authors selected R5 (Fig 1d) the most amyloidogenic repeat of the CsgA unit of curli28 (the detailed solid-phase synthesis is . . .
  

   

  

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