Systematic analysis of low-affinity transcription factor binding site clusters in vitro and in vivo establishes their functional relevance

HIGHLIGHTS

• who: Amir Shahein from the Institute of Bioengineering, School of Engineering, u00c9cole Polytechnique Fu00e9du00e9rale de Lausanne, Lausanne, Switzerland have published the research: Systematic analysis of low-affinity transcription factor binding site clusters in vitro and in vivo establishes their functional relevance, in the Journal: (JOURNAL) of 22/06/2022
• what: The authors characterize compositions of weak sites (W) and very-weak sites (V), in the range of one, or two orders of magnitude lower affinity than the consensus site, respectively.

SUMMARY

The bulk of existing research on TF-DNA interactions has . . .

 



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