HIGHLIGHTS
- who: Gregory A. Cary from the Mellon University, Pittsburgh, PA, USA have published the research work: Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: Using this network comparison, the authors show how bimodal switches in signaling pathways permit an evolutionary transition in regulatory network topology, and how such a transition is buffered by the presence of conserved regulatory kernels. The authors show that Tgif also positively regulates hesC expression specifically in the sea star mesoderm . . .
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