Systematic identification of tubulin-interacting fragments of the microtubule-associated protein tau leads to a highly efficient promoter of microtubule assembly

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  • who: Caroline Fauquant from the (UNIVERSITY) have published the research: Systematic Identification of Tubulin-interacting Fragments of the Microtubule-associated Protein Tau Leads to a Highly Efficient Promoter of Microtubule Assembly, in the Journal: (JOURNAL) of September/23,/2011
  • what: The aim of this work was the identification of Tau fragments that bind to tubulin or MTs to facilitate structural studies and to dissect the mechanism by which Tau promotes MT assembly. The authors show that the Pro-rich and MTBR domains each bind weakly to MTs generated by linking two peptides from these regions . . .

     

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